WSU researchers have created HuT mice with human-like short telomeres, allowing for groundbreaking studies on aging, cancer, ...

Researchers at The University of Texas MD Anderson Cancer Center have identified a potential breakthrough in the fight ...

Led by WSU College of Pharmacy and Pharmaceutical Sciences Professor Jiyue Zhu, the research team has developed mice that have human-like short telomeres, enabling the study of cellular aging as it ...

Globally, scientists are working to unlock the secrets of extending human lifespan at the cellular level, where aging occurs gradually due to the shortening of telomeres–the protective caps at the ...

Globally, scientists are working to unlock the secrets of extending human lifespan at the cellular level, where aging occurs ...

“This is the first mouse model with truly humanized telomeres because telomerase isn’t expressed in adult tissues in this model,” Zhu said. “Our paper demonstrates that they exhibit human ...

thus validating human telomerase reverse transcriptase as an important target for the development of anti-neoplastic therapies. To determine whether disruption of hTERT catalytic function would ...

Memory decline and social functional impairment are common manifestations of accelerated aging in PD. The function of telomerase reverse transcriptase (TERT) and telomere length (TL) is abnormal in ...

They found evidence that telomerase has a protective, “moonlighting” role beyond its established function, that safeguards plant cells from damage caused by exposure to cosmic radiation during space ...