Humans do not express urate oxidase, but species that do express it tend to have low urate levels, so Garson et al. developed a polyethylene-glycol-modified recombinant mammalian urate oxidase ...
These can include: Xanthine oxidase inhibitors (decreases the production of urate) Uricase (breaks down urate to make it easier for the body to flush it out) Uricosuric agents (increase amount of ...
Perspective from David A. McLain, MD, MACR, FACP, FRCP Colchicine for gout flare prophylaxis reduces the risk for cardiovascular events among patients initiating urate-lowering therapy ...