This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

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BioViva’s journey in gene therapy began with its use of an adeno-associated virus (AAV) vector. The company’s lead gene therapy, BV-702, is AAV-based and is in preclinical development for ...

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Based on this, we have developed a new approach to enhance the efficiency of rAAV-mediated gene expression. This approach uses co-infection with a transgene-containing vector and a second vector ...

The purpose of this study was to define unique gene expression profiles in muscle biopsies from patients with MSA-positive ... for classifying muscle biopsies into each type and MSA-defined subtype of ...

SAN FRANCISCO—Kicking off J.P. Morgan week, Dyno Therapeutics announced that Roche has exercised its option to license a novel capsid for use in a gene therapy ... on non-human primates to ...

In a groundbreaking leap for medical research, scientists have successfully cultivated miniature human brain models in the unique microgravity ... a "viral vector"—to deliver gene therapy ...

Emerging and re-emerging vector-borne diseases are among the prime public health concerns across the world. These diseases are not directly transmissible among humans, but they spread when optimal ...

Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.

The MADS-box gene family is an important transcription factor family involved in floral organogenesis. The previously proposed ABCDE model suggests that different ...

Jan. 30, 2025 — The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was ...