From 1979-85, 2435 patients with a transient ischaemic attack or minor ischaemic stroke were randomly allocated to receive long term "blind" treatment with aspirin 600 mg twice daily (n = 815), ...

Objective: Parkinson’s disease (PD) is a progressive neurological disorder characterised by a large number of motor and non-motor features that can impact on function to a variable degree. This review ...

1 Institute of Brain and Behavior, Department of Psychiatry, University of Maastricht, Maastricht, The Netherlands 2 Department of Radiology, Academisch Ziekenhuis Maastricht, Maastricht, The ...

Objective To analyse data from two previously published individual studies and two meta-analyses of the Ascertain Dementia 8 (AD8) cognitive screening instrument to calculate the recently described ...

Background Biological ageing is one of the principal risk factors for neurodegenerative diseases. It is becoming increasingly clear that acceleration of DNA methylation age, as measured by the ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting the upper and lower motor neurons. A key clinical feature of ALS is the absence of accurate, early-stage ...

Correspondence to Dr Masahiro Mori, Neurology, Chiba University Graduate School of Medicine School of Medicine, Chiba, Chiba, Japan; morim{at}faculty.chiba-u.jp Objective To investigate longitudinal ...

1 Department of Neurology, Westmead Hospital and Western Clinical School, University of Sydney, Sydney, Australia 2 Prince of Wales Medical Research Institute and Prince of Wales Clinical School, ...

Correspondence to Professor Yong-Ping Chen, Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Yongping.chen{at}wchscu.cn Background Alzheimer’s disease (AD) is ...

Correspondence to Dr Timothy Rittman, Department of Clinical Neurosciences, University of Cambridge, Herchel Smith Building, Forvie Site, Addenbrooke's Hospital Site, Robinson Way, Cambridge CB2 0SZ, ...

Drugs used for therapeutic interventions either alone or in combination may sometimes cause unexpected toxicity to the muscles, resulting in a varying degree of symptomatology, from mild discomfort ...