The phase 1 trial is testing the safety tolerability, pharmacokinetics, and pharmacodynamics of PVT201 in healthy volunteers and patients.

The decision to terminate the HYPERION trial reflects a loss of clinical equipoise, making it unethical to continue the placebo-controlled study.

Associations between therapies and quality of life (QoL) in patients with generalized pustular psoriasis (GPP) can differ substantially.

Patients with ATTR-PN have a high rate of comorbidities and substantial direct healthcare and economic burdens, a study found.

AGEP can closely mimic generalized pustular psoriasis (GPP), requiring histopathologic confirmation and assessment of peripheral eosinophilia.

Daily supplementation of beta-hydroxy-beta-methylbutyrate (HMB) could improve overall daily activity in Duchenne muscular dystrophy (DMD), a study found.

A little more than a third (36.1%) of patients with Huntington disease (HD) and chorea are taking an anti-chorea medication, a study found.

Surgical resection significantly improved overall survival and cancer-specific survival in primary central nervous system lymphoma (PCNSL).

TDP43 seems to worsen the inflammatory activation of astrocytes in neuromyelitis optica spectrum disorder (NMOSD), a study found.

Patients with combined diagnoses of ATTR-CM and aortic stenosis were at an increased risk of hospitalization and death, a study found.

The chronic lymphocytic leukemia (CLL) care team often takes a multidisciplinary approach, with specialists and healthcare professionals collaborating to provide a comprehensive, personalized ...

The original Rai system classification was divided into 5 stages from 0 to IV. The updated system now divides the disease into 3 stages 3: ...