structure, and molecular profile information of disease-relevant targets – as well as the criteria that make for a successful antibody molecule, like affinity, specificity, and developability ...

Oligonucleotide therapies are among the most promising biological therapeutics. They target disease at a different stage of ...

Fresh off winning a Nobel Prize last year, and previously tackling antibodies and peptides, the University of Washington’s David Baker and his team aim to make another breakthrough in art | As an ...

Stanford scientists discovered that a harmless skin bacterium triggers a powerful immune response. By tweaking a bacterial ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

Learn how analytical methodologies can be used to identify RSV pre- and post-fusion proteins for vaccine development.

In the rapidly advancing field of molecular biology, techniques for studying protein interactions are constantly evolving. Among these, Surface Plasmon Resonance (SPR) stands out as a powerful ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

A scientific breakthrough that could reshape biology as we know it is now at the center of a heated debate. Mirror bacteria, ...

P-cadherins are cell adhesion proteins that are overexpressed in cancers. This study offers insights into the regulation of cell adhesion and the design of drug delivery antibodies by showing that ...

The influenza A virus genome consists of eight segments of single-stranded, negative-sense viral RNA, which encode multiple ...