如今，一项新的研究确定了与T细胞沟通从而促使它们耐受、攻击或简单地忽略的特定肠道细胞类型，并解释了这些相反的反应是如何触发的。这一发现让科学家们对肠道免疫系统如何保持肠道平衡有了新的认识，并可能最终揭示 食物过敏 ...

A stable interaction between antigen-presenting cells (APC) and T cells is dependent not only on the absolute affinity between the T-cell receptor (TCR) and its ligand but also on the relative ...

Indeed, several groups have reported that overexpression of axin in APC-mutant cancer cells effectively reconstitutes the function of the destruction complex, indicating that there is no absolute ...

Cell-cell interactions help drive tolerogenic or inflammatory responses to the maelstrom of antigens passing through the gut.

To isolate immune cells, Lanna and his collaborators derived T cells and APC cells from the blood of human research participants, then cultured these cells. Then they exposed the cells to a mixture of ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

The police were finally able to get him into a set of Smith & Wesson designer bracelets when the APC stalled on its way to knock out yet another cell tower. Sounds like someone might have ...