Background and objectives Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of ...

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the ...

A PAT roadmap should address data analysis, aggregation, visualization, and the smart utility of those data for greater process understanding.

For example, CD4/CXCR4-expressing T cells that interact with cells expressing HIV-1-encoded envelope glycoproteins first manifest autophagy and then apoptosis. In this model, depletion of beclin-1 ...

Danés, principal investigator of the Cancer and Stem Cell Biology Lab at the Champalimaud Foundation, in Lisbon, has shown for the first time the important role of Survivin—a protein that has key ...

Apoptosis occurs in a wide range of human diseases. In animal models of virus-induced disease, apoptosis correlates with viral titre and can be found in areas targeted by viral infection, which ...

Beside developmental abnormalities, it may lead to tumorigenesis, autoimmunity, and other serious health problems. Deregulated apoptosis may also be the leading cause of cancer therapy chemoresistance ...

Double-stranded DNA levels were elevated in SLE. Apoptosis-derived membrane vesicles (AdMVs) from SLE sera had high ISG-inducing activity, which was diminished in cGAS-knockout or STING-knockout ...

This leap enabled systems like ChatGPT and Llama to dominate the AI landscape. However, the rise of AI model aggregators is now bringing long-overdue attention to the broader ecosystem, streamlining ...

DeepSeek uses an approach called test-time or inference-time compute, which slices queries into smaller tasks, turning each into a new prompt that the model tackles. Each step requires running a ...