ucl.ac.uk Results Dysregulated mitochondrial-associated gene expression correlated with increased ISG expression in JDM CD14+ monocytes. Altered mitochondrial-associated gene expression was paralleled ...

Jixin Zhong; Xiaoquan Rao; Jeffrey Deiuliis; Zachary Braunstein; Vimal Narula; Jeffrey Hazey; Dean Mikami; Bradley Needleman; Abhay R. Satoskar; Sanjay Rajagopalan ...

2 Immunology Research Core Facility – Gemelli Science and Technology Park (GSTeP) - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy 3 Division of Clinical Immunology, Fondazione ...

干细胞被称为医学界的“万用细胞”，因其具备自我更新和分化为多种细胞类型的能力，可用于修复和再生受损组织。它们在现代医学中发挥着重要作用，为疾病治疗和人类健康带来了新希望。间充质干细胞（MSC）因其来源丰富、安全性高，且具备免疫调节和 ...

Metastasis is a multistage process that requires cancer cells to escape from the primary tumour, survive in the circulation, seed at distant sites and grow. Each of these processes involves rate ...

Markers of immune cell lineage were also included: T cells (CD3, CD4, and CD8) and monocytes (CD14, CD11b, and CD163). The panel included chemokine receptors for signaling (CXCR4, CXCR3, CXCR5, and ...

Bovine γδ T cells, in addition to the cytokines and chemokines, express pathogen recognition receptors (TLR 1, TLR 2, TLR 3, TLR 4, TLR 7, TLR 8, and TLR 9), adaptor proteins (MyD88, TRAM, SARM), CD14 ...

Simultaneous measurement of surface proteins and gene expression within single cells using oligo-conjugated antibodies offers high-resolution snapshots of complex cell populations. Signal from ...

Tumor necrosis factor-α (TNF-α)-induced RIP1/RIP3 (receptor-interacting protein kinase 1/receptor-interacting protein kinase 3)-mediated necroptosis has been proposed as an alternative strategy ...

Innate lymphoid cells (ILCs) contribute to host defence and tissue repair but can induce immunopathology. Recent work has revealed tissue-specific roles for ILCs; however, the question of how a small ...