Agenus Inc. , a leader in immuno-oncology, today announced that BOT/BAL will be featured in two presentations at the upcoming American Association for Cancer Research (AACR) IO Annual Meeting that ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

1 SingHealth Translational Immunology and Inflammation Centre, SingHealth and Duke-NUS Graduate Medical School, Singapore, Singapore Objectives The imbalance between effector and regulatory T (Treg) ...

In this review, we first describe the structure, expression, and how the signaling pathways of CTLA-4 participate in reducing effector T-cell activity and enhancing the immunomodulatory ability of ...

Objective Regulatory T cells (Tregs) prevent autoimmunity and control inflammation. Consequently, any autoimmune or inflammatory disease reveals a Treg insufficiency. As low-dose interleukin-2 (ld-IL2 ...

1Department of Obstetrics and Gynecology, Peking University Third Hospital, China 2Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, China. 3Biobank, Peking ...

T-Mobile is the third-largest wireless carrier in the United States, with its popularity largely down to its network coverage and the wide range of tempting offers available. They span from T ...

The term 4×4 means a four-wheel-drive vehicle. Technically, the first digit is the number of wheels and the second is the number that are driven, so a four-wheel-drive pickup truck is a 4×4 ...

This Phase 1 study evaluated the safety and efficacy of botensilimab (BOT), an Fc-enhanced anti-CTLA-4 antibody ... downregulating intratumoral regulatory T cells, activating myeloid cells ...

Harvard Medical School research reveals highly specialized regulatory T cells that curb inflammation and act as gatekeepers to protect the inner regions of the brain. The work, which was done in mice, ...