与TAM非常相似，髓源性抑制细胞（MDSC）也可以通过CCL2–CCR2信号 ... 肿瘤和基质细胞产生CXCL12，它是趋化因子受体CXCR4的配体，由pDCs表达。

The stromal-derived factor-1 (SDF-1)/CXCR4 axis is a major determinant in the crosstalk between leukemic cells and BM stroma. In this study, we investigated the use of AMD11070, an orally ...

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...