In a paper published in National Science Review, an international team of scientists report a coordination nanomedicine ...

Tumor metastasis, recurrence, and therapeutic resistance are the main reasons for the failure of clinical cancer treatment. Studies have found that ...

Scientists have uncovered a mechanism for reinvigorating the immune system to stop it from flagging when it’s fighting ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

In vitro, EpCAM enhanced cancer cell stemness, as reflected by increased abilities of proliferation, self-renewal, migration and invasion, which was counteracted by arenobufagin. Furthermore ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis ... Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell, 38(2):229-246 (2020). DOI ...