(6) CAR-T cells are infused back into the patient, where they target and eliminate cancer cells expressing the CAR-specific antigen. CAR-T, chimeric antigen receptor-T. This review aims to present a ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Study Links Methylmalonic Acid to Weakening of Immune Cells in Lung Cancer Oct. 31, 2024 — A new study has found a surprising link between high levels of methylmalonic acid and the weakening of ...

Today, cancer has become one of the leading global tragedies. It occurs when a small number of cells in the body mutate, causing some of them to evade the body’s immune system and proliferate ...

The movement of connected cells contributes to morphogenesis, wound healing and cancer invasion and each process underlies homologous but distinct molecular mechanisms of cell–cell interaction ...

She had no family history of cancer. So when she experienced some swelling in her breast near the end of what she called “a textbook-easy pregnancy” with her third child, she and her doctors ...

If lung cancer spreads to the brain, it would be called primary lung cancer metastatic to the brain, or secondary brain cancer. In this case, the cancer cells in the brain would be lung cancer cells, ...

The experts have uncovered why cancer cells respond differently to radiotherapy, with some cells dying in ways that alert the immune system and others dying silently. This difference is linked to how ...

Scientists at Children's Medical Research Institute (CMRI) have solved a big mystery in cancer research – why cells die in different ways following radiotherapy. This surprising finding opens up ...

Breast cancer results from mutations in the genes of breast cells. The mutations cause the cells to divide and multiply uncontrollably. The exact cause of breast cancer is unknown, but some people ...

Glioblastoma is typically treated with photon radiation, which uses high-energy X-rays to destroy the DNA in cancer cells, thus killing them. Usually, patients' tumors are mapped out by MRI before ...