Malignant cells with high delta-like ligand 4 (DLL4) expression interact with cancer-associated fibroblasts and endothelial cells via the DLL4-NOTCH signalling pathway to metastasise from primary CRC ...

Dr. Weickert will present Pacylex at the OBIO® Investment Summit and Early Technology Showcase February 5-7, 2025, at the Arcadian Court & Loft, Toronto Mr. Kamdar will present Pacylex at the PWMC ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Mechanical factors influence the initial fate of cancer cells after they have left a primary tumour. Blood-flow patterns from the primary tumour determine which organ the cells travel to first.

Tumors contain a fraction of cancer stem cells that maintain the propagation ... We focused on the Notch pathway since Jagged-2, a Notch ligand was found to be overexpressed in the LSC samples.

Good news for the sector came January 23 when global pharmaceutical giant AstraZeneca plc announced an eye-popping $820 ...

Feb. 3, 2025 — Researchers have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune ... Study Establishes Link ...

Our objective was to culture these cells in order to understand them and exploit their therapeutic potential to the full. Design Here, hypothesising that some CTC potentially have cancer stem cell ...

A large research team led by nanotechnologist Roy van der Meel rebuilt the body's own proteins and fats into nano-delivery ...

“ID3+ T cells have the remarkable ability to resist burnout and maintain a powerful immune response over time, making them particularly effective in the face of chronic infections or cancer ...

A large research team led by nanotechnologist Roy van der Meel rebuild the body's own proteins and fats into nano delivery ...