UC San Diego researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease ...

Impact of the stem cell niche on aging: we study the communication between stem cells and their niche (e.g. neighbor cells, ECM) in multiple tissues including the intestine, mammary, skeletal muscle, ...

The Under-oil Open Microfluidic System enhances tumor cell-ECM interaction studies, improving anti-metastatic drug testing for triple-negative breast cancer.

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its ...

Organization of different cell types and the extracellular ... tissue regeneration or to hypertrophy and cancer. We investigate how the composition and dynamics of basement membrane, a specialised ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity ...

However, glial cells in the brain continue to divide throughout a mammal's adult life. Mammalian epithelial cells also turn over regularly, typically every few days. Whenever stem cells are called ...

Tendon stem cells differentiate into tenocytes (Zhang, 2010); the predominant cell type within tendon, responsible for producing extracellular matrix (ECM). The local stem cell environment (niche) is ...

Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease.