In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

(6) CAR-T cells are infused back into the patient, where they target and eliminate cancer cells expressing the CAR-specific antigen. CAR-T, chimeric antigen receptor-T. This review aims to present a ...

Basically, this is claimed to “starve” the cancer cells of some fuel and cause them to: grow more slowly decrease in size Contrary to the common myth, cancer cells can still grow on fats and ...

This means it's often next to impossible to avoid harming healthy cells, so oncologists are often unable to use as high a dose as they would like, says Loo. Cancer specialists have long believed ...

Ephrin A1 facilitates colonization and metastasis of gastric cancer cells in vitro and in vivo via inducing epithelial-mesenchymal transition (EMT). Ephrin A1 directly interacts with EGFR and induces ...

Because DNA damage can be fatal to cells, drugs that target PARP1 in cancer cells and arrest DNA repair by fixing the glue in its “solid” form might kill them. Organizing complex biochemical ...

In a significant step forward for India’s cancer treatment, Immuneel Therapeutics, a leading cell and gene therapy statrtup backed by entrepreneur Kiran Mazumdar-Shaw, has unveiled Qartemi, the ...

Theerawut et al. demonstrate that HA allows breast cancer cells to return to a stem cell state via EMT by modulating the TGF-β network (20). Recent studies have shown that using different molecular ...

By identifying key interactions between this common oral bacterium and host cells, the research ... bacterial infection and promote epithelial-mesenchymal transition (EMT), a process crucial ...