Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

Subsequently, to confirm the construction of the adenovirus vector vaccine rAd-TB4, we analyzed its protein expression using western blotting ... route of administration and dose to establish the ...

Thus, the peptide dimer causes an aggregation that resembles the HAP induced aggregation of the core protein and, like CAMs, can be expected to have the potential to disrupt the HBV life cycle. The ...

Commercially available therapeutic lipidated GLP-1 analogues ... During the 6 days of sample aging, several lipidated analogues formed aggregates with variable morphologies ranging from elongated ...

Caíque de Abreu/Getty Images A new study has identified a protein that helps drive bladder ... Researchers found that a combination therapy of two drugs disrupts this pathway, helping to suppress ...

Protein aggregation is the process by which misfolded proteins adopt a conformation that cause its polymerization into aggregates and organized fibrils. Many neurodegenerative diseases ...

The study is among the first to show that the rotavirus protein NSP4 is both necessary ... "Although oral rehydration therapy and live-attenuated rotavirus vaccines have helped reduce the burden ...

The 2 nd Gene Therapy Immunogenicity Summit is the industry’s definitive forum enabling you to better modulate, measure and predict immune response to your gene therapy candidate.

These aggregates can compromise product efficacy, elevate immunogenicity risks and complicate purification strategies. This whitepaper explores how innovative chromatography solutions can improve ...