Renal fibrosis is one of the main pathological features of chronic kidney disease (CKD), and its treatment has been a hot research topic ... and some natural products or Chinese medicines can be used ...

Skin fibrosis is an often-painful condition wherein the skin thickens and hardens, making it difficult to move. And with no effective treatments currently available, patients are left with few avenues ...

In its early stages, kidney disease may not cause any symptoms or signs. However, as it progresses, it can cause symptoms such as itchy skin, pruritus, and a rash. Around 35.5 million adults in ...

iDivision of Nephrology, Department of Medicine, O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada jDepartment of Community Health Sciences, O ...

Department of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu 610041, China College of Polymer Science and Engineering, College of Biomedical Engineering, State ...

and fibrosis in MCD-fed mice. Furthermore, SOX9 deletion inhibited AMPK pathway activation, while SOX9 overexpression enhanced it. Notably, administration of an AMPK inhibitor negated the ...

Although the relationship between Sgsm2 and kidney disease has not been described in the literature, this protein may be related to the EMT that occurs in renal fibrosis in patients with CKD (Figure ...