Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...

肝脏巨噬细胞在调节肝细胞代谢和维持肝脏免疫耐受方面发挥核心作用。正常生理条件下，肝脏巨噬细胞倾向于 M2 表型，可通过分泌白细胞介素（IL）-4 和 IL-13 抑制炎症。然而，在 NAFLD 进展时，肝星状细胞激活、血液中脂多糖水平升高以及 FFA 激活炎症小体等变化，会刺激炎症发生，增加分泌促炎细胞因子的 M1 巨噬细胞比例。

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Macrophages are the primary cells responsible for nanoparticle processing and ...