VolitionRx Limited ("Volition"), a multi-national epigenetics company, today announced the results of a large-scale study which shows that its Nu.Q®NETs H3.1 biomarker is an independent predictor of ...

Moreover, immunogenic complexes composed of MMP-9 and anti-MMP-9 were identified in SLE sera. These complexes, as well as anti-MMP-9 autoantibodies, induced NETosis and enhanced MMP-9 activity.

细菌性肺炎是一种严重的公共卫生负担，它不仅导致了大量的发病率和死亡率，还带来了沉重的医疗成本。尽管抗生素和辅助治疗是目前的主要治疗手段，但对于疾病发病机制的深入理解仍然有限。

Protein lactylation is a new form of post-translational modification that has recently been proposed. Lactoyl groups, derived mainly from the glycolytic product lactate, have been linked to protein ...

Study of the genetics of rheumatoid arthritis (RA) began about four decades ago with the discovery of HLA-DRB1. Since the beginning of this century, a number of non-HLA risk loci have been identified ...

College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, P. R. China ...

Rationale: Acute kidney injury (AKI) is a clinical syndrome associated with a multitude of conditions. Although renal replacement therapy (RRT) remains the cornerstone of treatment for advanced AKI, ...

未成熟的中性粒细胞表现出PADI4的高表达，这是一种与NETs（NETosis；中性粒细胞胞外陷阱的形成）有关的关键因素。最近的研究表明，NETs与严重感染 ...