A new study from researchers at Weill Cornell Medicine-Qatar (WCM-Q) reveals how the SARS-CoV-2 virus evolved from initially ...

Background De novo mutations (DNMs) are linked with many severe early-onset disorders ranging from rare congenital malformation to intellectual disability. Conventionally, DNMs are considered to have ...

and two Omicron-based variants. To assess their binding with the hACE2 receptor, the scientists considered the energetic contribution of amino acids and simulated a projection of the effect of certain ...

"The participants had been vaccinated multiple times, including with the then-current vaccine that was effective against Omicron XBB.1.5." Using reverse mutational scanning, the researchers identified ...

While the virus is generally found in wild birds and poses risk only to poultry, its spread to a new range of mammals may pave the way for new mutations that could increase its lethality. In 2024, the ...

Department of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China Shanghai Engineering Research Center of ...

Central to this is our very own Dr Strangelove who identifies as Prof Tulio de Oliveira and who, despite the Meatloaf hairstyle and the link with a now discredited university, is the man who first ...

In a family of 15 people in northern Italy, six developed late-onset Alzheimer’s disease – and when researchers ran genetic tests, all six had a rare mutation in a protein-coding gene known as ...

The virus, which has primarily affected poultry populations worldwide, is now spreading rapidly among humans and has been showing signs of concerning mutations. A recent CDC report revealed that ...

In an analysis of multimodal data from 9,331 human individuals, we found that CpG mutations indeed coincide with changes in methylation, not only at the mutated site but with pervasive remodeling of ...

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.