Background: A study was undertaken to validate the modified American Thoracic Society (ATS) rule and two British Thoracic Society (BTS) rules for the prediction of ICU admission and mortality of ...

Background Newborn bloodspot screening (NBS) for cystic fibrosis (CF) was introduced across the UK in 2007 but the impact on clinical outcomes and health inequalities for children with CF is unclear.

2 Department of Pulmonary and Cardiac Rehabilitation, Coventry University, School of Health and Life Sciences, Coventry, UK 3 Clinical Trials Unit, Warwick Medical School, The University of Warwick, ...

Background The natural history and time course of the onset of exacerbation events of chronic obstructive pulmonary disease (COPD) is incompletely understood. Methods A prospective cohort of 212 ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

The pathophysiology of residual sleepiness in treated obstructive sleep apnoea (OSA) remains poorly understood. Animal models ...

2 Department of Medicine, University of Cambridge, Addenbrookes' Hospital, Cambridge, UK 3 Department of Gastroenterology, University of Buckingham, Ealing Hospital NHS Trust, Southall, UK 4 ...

Correspondence to Dr Sami O Simons, Department of Respiratory Medicine, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands; sami.simons{at}mumc.nl Coronavirus SARS-CoV-2 is ...

1 Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan 2 Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, ...

Rationale There are no population-based studies from sub-Saharan Africa describing longitudinal lung function in adults. Objectives To explore the lung function trajectories and their determinants, ...

Department of Psychiatry, Prince of Wales and Shatin Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong Dr A M Li, Department of Paediatrics, Prince of Wales Hospital, The Chinese ...

3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...