2011年5月31日 · Bone regeneration is a complex, well-orchestrated physiological process of bone formation, which can be seen during normal fracture healing, and is involved in continuous remodelling throughout adult life.

Bone regeneration is a complex process that involves several interacting biologic mechanisms and is a critical component of many aspects of musculoskeletal care, including fracture healing, spinal fusion, and osteointegration of implants.

The crucial role of bone in mammalian physiology is further highlighted by the body’s unique ability to repair bone through regeneration, restoring it to a fully functional, pre-injury state. Studies have shown that a regulated balance of activity between bone-forming osteoblasts and bone-resorbing osteoclasts — the two main cellular ...

In this review, we describe the options available for bone regeneration, focusing on tissue engineering strategies based on the use of different biomaterials combined with cells and growth factors. Keywords: bone regeneration, tissue engineering, scaffolds, mesenchymal stem cell, bio-materials. 1. Bone Biology: Structure and Composition

2023年1月9日 · This Review discusses the complex processes underlying bone regeneration, focusing on the early healing phase and its highly dynamic environment, where vibrant changes in cellular and tissue ...

2023年8月16日 · Innovative biomaterials that allow the coordinated and well-controlled repair of bone fractures and bone loss are being designed to reduce the need for autologous or allogeneic bone grafts eventually.

Bone has a remarkable endogenous regenerative capacity that enables scarless healing and restoration of its prior mechanical function, even under challenging conditions such as advanced age and metabolic or immunological degenerative diseases.