Those who develop electron microscope techniques and explore new methods in the study of cells, normal as well as malig­nant, probably do contribute more actively to cancer research than those who seek spectacular answers by routine techniques of electron micros­copy applied to innumerable specimens.

The electron microscope reveals much more information on tumor cell structure than can be obtained with the light microscope, and some of the data are useful in diagnostic studies. In this review, major contributions of electron microscopy in the main tumor categories are discussed.

2021年10月6日 · Here we present a volume EM atlas at such resolution comprising ten three-dimensional datasets for whole cells and tissues, including cancer cells, immune cells, mouse pancreatic islets and...

The aim of this study was to investigate using the scanning electron microscopy (SEM) how the highly invasive MDA-MB-231 breast cancer cells, interplaying with ECM substrates during cell migration/invasion, modify their morphological characteristics and cytoplasmic processes in relation to their invasive potential.

The aim of the present study was to examine the morphology of spheres isolated from PANC-1 human pancreatic cancer cells via scanning electron microscopy (SEM) and transmission electron microscopy (TEM). PANC-1 cells formed round to irregular oblong spheres within 1 week following seeding in ultra-low-attachment plates.

To explore morphological features of circulating tumor cells (CTCs) and tumor-derived extracellular vesicles (tdEVs), we developed a protocol for scanning electron microscopy (SEM) of CTCs and tdEVs. CTCs and tdEVs were isolated by immunomagnetic ...

In the oncological field, the identification of protein structure and protein interaction by cryo-EM is emerging with new and surprising possibilities for comprehension of the molecular mechanisms involved in cancer development.

2020年5月21日 · How to observe cancer cells under a microscope. A variety of microscopy techniques can be used to observe cancer cells, such as by using an electron microscope, or even a light microscope. What’s important to remember, however, is that certain films and staining techniques are required to view the cancer cells properly.

2018年10月31日 · To explore morphological features of circulating tumor cells (CTCs) and tumor-derived extracellular vesicles (tdEVs), we developed a protocol for scanning electron microscopy (SEM) of CTCs and tdEVs. CTCs and tdEVs were isolated by immunomagnetic enrichment based on their Epithelial Cell Adhesion Mo …

An electron microscopic study of the invasion of ascites tumor cells into the abdominal wall