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ImmixBio Announces FDA Orphan Drug Designation for IMX-110 …
2021年9月30日 · IMX-110 is a Tissue-Specific Therapeutic TM built on ImmixBio's TME Normalization TM Technology encapsulating a poly-kinase inhibitor and apoptosis inducer delivered deep into the tumor...
Immix Biopharma Announces Early Positive IMX-110 Interim …
2023年5月3日 · IMMINENT-01 is a first-of-its-kind, ongoing phase 1b/2a clinical trial combining tissue specific therapeutic IMX-110 with BeiGene / Novartis' anti-PD-1 antibody tislelizumab, in patients with advanced solid tumors.
Immix Biopharma Announces 16th Patient Dosing in Ongoing …
2022年12月20日 · 16 th patient dosed with IMX-110 to date; This is the second patient dosed with IMX-110 in December 2022; Patients undergo CT scans every 8 weeks after dosing to assess tumor response to IMX-110; clinical data expected to …
IMX-110 + anti-PD-1 Combination Produced Extended Median
2022年1月25日 · Our lead asset IMX-110, currently in Phase 1b/2a clinical trials, holds orphan drug designation (ODD) by the FDA for soft tissue sarcoma, and has received Rare Pediatric Disease Designation (RPDD) for the treatment of rhabdomyosarcoma, a life-threatening form of cancer in children.
IMX-110/Tislelizumab Yields Notable Tumor Shrinkage in Two …
2023年5月5日 · Investigational agent IMX-110 plus tislelizumab resulted in tumor shrinkage at 2 months in patients with advanced metastatic colorectal cancer (CRC), according to a press release on interim data from the phase 1b/2a IMMINENT-01 trial.
Immix Biopharma Announces Early Positive IMX-110 Interim …
2023年5月3日 · Immix Biopharma Announces Early Positive IMX-110 Interim Clinical Trial Data Demonstrating 100% Tumor Shrinkage in Advanced Metastatic Colorectal Cancer at the Lowest Dose of IMX-110 + BeiGene...
Immix doses first patient in US in its phase 1b/2a trial in patients ...
Immix Biopharma announced that the first patient in the USA was dosed successfully in its flagship phase 1b/2a clinical trial testing Imx-110 in patients with refractory solid tumors. To-date, the trial has accrued patients across tumor types.
ImmixBio Initiates IMX-110 GMP Manufacturing Scale-Up,
LOS ANGELES, Jan. 31, 2022 (GLOBE NEWSWIRE) -- Immix Biopharma, Inc. (Nasdaq: IMMX) (“ImmixBio”, “Company”, “We” or “Us”), a biopharmaceutical company pioneering Tissue-Specific Therapeutics (TSTx)...
Immix Biopharma Announces Patient Dosing in Ongoing Phase 1b/2a IMX-110 ...
2022年12月13日 · IMX-110 monotherapy and IMX-110 combination clinical trial with Beigene/Novartis anti-PD-1 tislelizumab are enabled by newly manufactured, scaled-up IMX-110 GMP batches produced using our proprietary process.
IMX-110 Plus Tislelizumab Shows Early Activity in Advanced
2023年5月3日 · Immix Biopharma announces early positive IMX-110 interim clinical trial data demonstrating 100% tumor shrinkage in advanced metastatic colorectal cancer at the lowest dose of IMX-110 + BeiGene /...
ImmixBio Announces Positive IMX-110 Phase 1b/2a Interim …
2022年1月19日 · Our lead asset IMX-110, currently in Phase 1b/2a clinical trials, holds orphan drug designation (ODD) by the FDA for soft tissue sarcoma, and has received Rare Pediatric Disease Designation...
ImmixBio Announces Positive IMX-110 Phase 1b/2a Interim …
2022年1月19日 · Our lead asset IMX-110, currently in Phase 1b/2a clinical trials, holds orphan drug designation (ODD) by the FDA for soft tissue sarcoma, and has received Rare Pediatric Disease Designation (RPDD) for the treatment of rhabdomyosarcoma, a life-threatening form of cancer in children.
IMX-110 Granted Rare Pediatric Disease Designation by FDA …
2022年1月5日 · The FDA has granted a rare pediatric disease designation to IMX-110, qualifying the treatment to receive priority review and a fast track designation voucher, for pediatric patients with life threatening rhabdomyosarcoma. 1
Immix Biopharma Announces Early Positive IMX-110 Interim
2023年5月3日 · IMMINENT-01 is a first-of-its-kind, ongoing phase 1b/2a clinical trial combining tissue specific therapeutic IMX-110 with BeiGene / Novartis’ anti-PD-1 antibody tislelizumab, in patients with...
curcumin/doxorubicin-encapsulating nanoparticle IMX-110
Upon administration of the curcumin/doxorubicin-encapsulating nanoparticle IMX-110, the curcumin moiety targets and inhibits the activation of STAT3 and NF-kB and prevents STAT3- and NF-kB-mediated signaling pathways, both of which are activated in a variety of human cancers and plays a key role in neoplastic transformation, uncontrolled tumor ...
Immix Biopharma Doses Additional Patients in Ongoing Phase
2023年1月13日 · IMX-110 clinical trial data is expected to be released on a rolling basis beginning in Q1 2023; once dosing begins, patients undergo CT scans every 8 weeks to assess tumor response to IMX-110.
FDA Approves Rare Pediatric Disease Designation for IMX-110 for ...
2022年1月19日 · IMX-110, a tissue-specific therapeutic designed to accumulate at intended therapeutic sites at 3 to 5 times the rate of conventional therapeutics, has already received Orphan Drug Designation for the treatment of soft tissue sarcoma.
Immix Biopharma — IMX-110 interim results in colorectal cancer
2023年7月19日 · Immix Biopharma is developing a new class of tissue-specific therapeutics targeting oncology and immune-dysregulated disease. Its lead asset, IMX-110, is being investigated in a Phase Ib/IIa study for the treatment of soft tissue sarcoma and a Phase Ib trial in advanced solid tumors in combination with the ICI tislelizumab.
ImmixBio Announces Positive IMX-110 Phase 1b/2a Interim
2022年1月19日 · Our lead asset IMX-110, currently in Phase 1b/2a clinical trials, holds orphan drug designation (ODD) by the FDA for soft tissue sarcoma, and has received Rare Pediatric Disease Designation...
ImmixBio Initiates IMX-110 GMP Manufacturing Scale-Up ... - BioSpace
2022年1月31日 · Immix Biopharma, Inc. today announced that it has initiated IMX-110 Good Manufacturing Practice (“GMP”) scale-up manufacturing, potentially accelerating the timeline to clinical data from two ImmixBio clinical trials planned for 2022.
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